Abstract:
Protein functions and characteristics can highly differ from physiological conditions in presence of chemical, mechanical or electromagnetic stimuli. In this work we prov...View moreMetadata
Abstract:
Protein functions and characteristics can highly differ from physiological conditions in presence of chemical, mechanical or electromagnetic stimuli. In this work we provide a rigorous picture of electric field effects on proteins behavior investigating, at atomistic details, the possible ways in which an external signal can be transduced into biochemical effects. Results from molecular dynamics (MD) simulations of a single superoxidismutase (SOD) enzyme in presence of high exogenous alternate electric fields will be discussed.
Published in: 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Date of Conference: 28 August 2012 - 01 September 2012
Date Added to IEEE Xplore: 10 November 2012
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PubMed ID: 23367217