Abstract:
A novel electrokinetic approach using single-phase electrorotation for the label-free manipulation and characterization of biological cells is presented. A single shell m...Show MoreMetadata
Abstract:
A novel electrokinetic approach using single-phase electrorotation for the label-free manipulation and characterization of biological cells is presented. A single shell model was used to theoretically design and develop an experimental strategy for biological particle characterization. As a study model, electro-rotation of glutathione agarose (GA) beads was studied using three- dimensional spatially oriented micro-needle setup. Effect of electrical parameters (i) voltage: from 0–10 Vpp and (ii) frequency: 0–100 MHz was evaluated on a heterogeneous mixture of GA beads (35–150 microns). The relationship of the electrical parameters to rotational frequency of the beads was studied. This paper demonstrates a simple and easy to implement prototype for electrokinetic characterization of particles with translational potential for biological cells.
Published in: 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Date of Conference: 26-30 August 2014
Date Added to IEEE Xplore: 06 November 2014
Electronic ISBN:978-1-4244-7929-0
ISSN Information:
PubMed ID: 25571112