Abstract:
Compared with clinical and experimental approaches, numerical modeling of defibrillation offers a great opportunity to optimize the defibrillation strategy in a more indi...Show MoreMetadata
Abstract:
Compared with clinical and experimental approaches, numerical modeling of defibrillation offers a great opportunity to optimize the defibrillation strategy in a more individualized way. Through numerical simulation of the shock-induce electric field distribution, the outcome of a certain defibrillation shock could be predicted according to several different metrics. In this paper, we propose a novel evaluation method, in which four defibrillation criteria are assigned with separate weighting factors to quantitatively assess the efficiency of a certain defibrillation shock. Three anatomically realistic finite element models of swine were constructed for the evaluation study of 8 electrode pairs in different placements. In addition, corresponding animal experiments were performed to determine the defibrillation threshold of 8 electrode placements. Both computational and experimental results suggest that the clinical recommended anterior-lateral position is the most efficient electrode displacement for transthoracic defibrillation in swine. In conclusion, the good agreement between stimulations and experiments indicates that the present multi-criteria evaluation method would be potentially useful for optimizations of cardiac defibrillation outcome.
Published in: 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Date of Conference: 25-29 August 2015
Date Added to IEEE Xplore: 05 November 2015
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PubMed ID: 26737296