Abstract:
The purpose of this study is to identify a set of radiomic features extracted from apparent diffusion coefficient (ADC) maps, obtained using baseline diffusion weighted m...Show MoreMetadata
Abstract:
The purpose of this study is to identify a set of radiomic features extracted from apparent diffusion coefficient (ADC) maps, obtained using baseline diffusion weighted magnetic resonance imaging (DW-MRI), which are able to predict the outcome of induction chemotherapy (IC) in sinonasal cancers. Such prediction could help the clinician defining the better treatment for a particular patient. Eighty-eight radiomic features were extracted from the ADC maps of 15 patients that underwent IC. A preliminary filtering of the features was made by assessing their stability to geometrical transformations of the region of interest (ROI). Mann-Whitney tests corrected for control of false discoveries were performed to identify the features that could discriminate between responsive and non-responsive patients (4 and 11 respectively). Twenty features were found to be able to discriminate the two groups and they can potentially be used for prediction of response to treatment.
Published in: 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Date of Conference: 18-21 July 2018
Date Added to IEEE Xplore: 28 October 2018
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PubMed ID: 30440511