The effect of temperature on energy and binding energy of polyimide-nano a-Al2O3 were simulated by molecular dynamics. The simulation results show that the changes of temperature don't infulence the interaction nature of polyimide-nano a-Al2O3, and binding energy of polyimide-nano a-Al2O3 changes slightly in the range of 298K to 648k. These indicate that system of polyimide-nano a-Al2O3 is steady, and coincide with the property that system of polyimide-nano a-A12O3 has wide range of working temperature.