In this paper, we describe a SOA-based middleware to integrate Internet-of-Things technologies in industrial setups. The middleware allows a seamless horizontal integration among heterogeneous technologies and vertical integration with applications and business systems. Using the middleware, we evaluated an approach to improve the reliability of 6LoWPAN-based sensor networks with self-configuration and self-healing capabilities to support an innovative monitoring and control framework in a manufacturing line. The sensor networks were evaluated in a test bed consisting of various physical devices that emulates a welding station.