Weapon system selection is a critical task for commanders because weapon systems have become the primary deciding factor to determine the results of battles. Weapon system evaluation and selection problem is usually regarded as a multiple attribute decision-making(MADM) problem under fuzzy environment. Therefore, a hybrid fuzzy MADM methodology is proposed to deal with weapon system selection in this paper. The entropy weighting method is employed to determine the importance weights of evaluation attributes. Then fuzzy TOPSIS approach is utilized to identify the overall performance values and ranking order of alternative weapon systems. Finally, a case study on missile system selection is given to demonstrate the usefulness and effectiveness of the proposed methodology.