The research on 6G in the EU-funded flagship project Hexa-X started with the investigation of the most important technology enablers and the evaluation of relevant 6G use cases. The next step is to integrate these enablers in a 6G E2E architecture that fulfills all use case-based Key Performance (KPI) and Key Value Indicators (KVI) and that follows the guidelines of general architectural principles. In addition, the main focus of an E2E 6G architecture must be on security and sustainability which both will have increased importance for future communication networks and society.