Abstract:
Competing endogenous RNAs, or ceRNAs, are sets of RNAs including mRNAs that can regulate each other by competing for microRNAs binding. ceRNAs form another level of regul...Show MoreMetadata
Abstract:
Competing endogenous RNAs, or ceRNAs, are sets of RNAs including mRNAs that can regulate each other by competing for microRNAs binding. ceRNAs form another level of regulation across the transcriptome and thus expand the function of microRNAs. CeRNAs have been shown to play important roles in disease like cancer [1]. Despite the importance, there does not yet exist a systematic tool for identifying ceRNAs. In this work, we propose and develop, TraceRNA, a computational tool and an online application to assist the exploration of ceRNAs.
Published in: Proceedings 2012 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS)
Date of Conference: 02-04 December 2012
Date Added to IEEE Xplore: 25 April 2013
ISBN Information: