The Web of Things (IoT) is critical for the virtual change in medication because it provides innovative business models to facilitate and promote improvements in practice operations, control costs, enhance productivity, and improve patients’ experiences. The use of innovative IoT techniques in personalized health, however, remains incredibly challenging due to several issues, such as incoherent IoT program structures, diversity among connected wearable devices, a lack of accurate and affordable smart medical sensors, the complexity of the generated data, and an increased need for interoperability. This research delves at the history of IoT in healthcare, with a focus on how these technologies are being used to the rapidly expanding area of personalized medicine. It covers both common health scenarios and cutting-edge, intricate methods generated from the Internet of Things. It highlights the scientific, ethical, and economic challenges of developing a better medical system for early illness detection. At long last, the Web of Things (IoT) is permitting present-day medication to answer the requests rapidly of the time by creating a platform for communication across different health sectors, providing digital help at every stage, and so on.