Neural cell type recognition between globus pallidus externus and globus pallidus internus by Gaussian mixture modeling | IEEE Conference Publication | IEEE Xplore

Neural cell type recognition between globus pallidus externus and globus pallidus internus by Gaussian mixture modeling


Abstract:

This paper proposes a new application of Gaussian mixture modeling (GMM) for neural cell type classification between globus pallidus externus (GPe) and globus pallidus in...Show More

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Abstract:

This paper proposes a new application of Gaussian mixture modeling (GMM) for neural cell type classification between globus pallidus externus (GPe) and globus pallidus internus (GPi). Our work is motivated by the results of previous research in which different neural cell types could be identified by their discharge patterns. It is critical for surgeons to distinguish between these two cell types to identify brain nuclei during the procedure known as a pallidotomy, a treatment for Parkinson's disease. Currently, skilled surgeons rely on discharge patterns converted to sound. In this study, performance evaluations are conducted based on a labeled database recorded during previous neural surgeries. The GMM achieves better than 92% correct recognition using 10-second segments, which demonstrates the best performing classifier to date.
Date of Conference: 23-23 March 2005
Date Added to IEEE Xplore: 09 May 2005
Print ISBN:0-7803-8874-7

ISSN Information:

Conference Location: Philadelphia, PA

First Page of the Article


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