In this work, the development and implementation of an electronic nose system based on nano-composite polymer gas sensors for human odor detection and tracking health status are proposed. To evaluate the performance of gas sensors, we have performed tests from human odor including breath and urine. The results show that our lab-developed gas sensors have an excellent performance to detect the volatile that released from the human body. The discrimination ability of the electronic nose evaluated by principal component analysis (PCA) could successfully classify and discriminate volunteers into healthy and diabetes groups.