Control Cyber-Physical Systems (CPS) is a major category of CPS. In control CPS, besides the well-studied noises within the physical control subsystem, we are particularly interested in better understanding cross-domain noises: those come from the “physical” control subsystem, propagate through the “cyber” computing subsystem, and go back to the physical subsystem. The focus of this paper is to propose a framework to profile the propagation of cross-domain noises.