Aiming at the problem that the existing end-to-end automatic codec wireless communication systems do not perform well in multipath channel, this article proposed an improved auto-codec end-to-end wireless communication system. In this article, by changing the size of the convolution kernel, two dimensional(2-D) convolution is used to combat the frequency selective fading caused by the multipath effect, and the traditional OFDM module is combined with the auto-codec, so as to improve the ability of the system to cope with multipath. Simulation results show that the performance of the proposed 2-D convolution based self-codec end-to-end wireless communication system is improved by 17% and 60%, respectively, compared with the one dimensional(1-D) convolution self-codec wireless communication system and the traditional OFDM communication system in 5-path Rayleigh channel and 64QAM modulation.