A novel probabilistic depth-guided multi-view denoising (PDMD) algorithm is proposed in this work. We formulate the multi-view image denoising problem by considering the uncertainties in depth estimates in noisy environments. Specifically, we employ the geometric distributions of nonlocal neighbors, as well as the block similarities, to approximate the probabilities of depth estimates. We then use those probabilities to average all nonlocal neighbors and perform the minimum mean square error (MMSE) denoising. Simulation results show that the proposed PDMD algorithm provides better denoising performance than conventional algorithms.