In this paper we have proposed a system that will be able to analyze the Optimum Crop Cultivation of Bangladesh based on the knowledge of Neuro-Fuzzy System (NFS). The Neuro-fuzzy system is the collection of two techniques: fuzzy logic and the neural network. The system can compute the yield of a certain crop by using the value of humidity, temperature and rainfall. By using this system farmer will be able to increase agricultural productivity. Hence, this will have an overwhelming impact on poverty alleviation, boosting employment rate, human resource development and food security. The dataset that we used to train our system was collected from the official website of Bangladesh Bureau of Statistics. It contains the humidity, temperature and rainfall values of thirty-three districts of Bangladesh that produced the most crops from the year 2007-2013. We considered a few major crops of Bangladesh, i.e., Rice (Aus, Amon, Boro), Wheat and Potato. By using this system, farmers can harvest maximum production of crops throughout the various seasons in the year.