This paper proposes a new texture description metric, the color distribution evenness (CDE) measure, and discusses its usage of performing multi-scale texture analysis. Further, CDE measure is applied to color-texture segmentation of natural images, upon which we propose the ISBEC (Image Segmentation Based on the distribution Evenness of Colors) algorithm. Experiments verify the effectiveness of CDE measure for texture analysis and that of ISBEC for color-texture segmentation.