In order to satisfy the character of multi-sensor system which has a large amount of data and strict requirement of real time response, a module based on FPGA & DSP is designed for multi-sensor information processing and fusion after considering that FPGA (EP2C8T144C8N) has high-speed, complex logic control ability and floating-point DSP (TMS320C6713B) has high-speed, complex data processing capability. FPGA controls interface and timing of the sensor signal acquisition, pre-processes data and transfers the data to DSP in parallel, which can simplify the peripheral circuit and ensure the real-time performance of the system; Data processing is realized in DSP, and DSP is used as main control chip to manage the system operation and communicate with the host computer. The system combines the best advantages of FPGA and DSP, and its structure is suitable for modular design and has strong versatility. Finally the system is applied to solid phase concentration measurement of the multiphase flow. The experimental results show that the method has great advantages over traditional methods in computing precision and speed.