This paper presents an overview and experimental analysis of the MC SPWM techniques for single-phase cascaded H-bridge inverter. The multilevel power converters are an alternative to traditional converters known as “three-level converters”. The voltage waveforms and the related frequency spectra, which have been obtained by simulation analysis in Matlab-Simulink environment, are here reported for all the proposed modulation techniques. The simulation results have been experimentally validated through means of a DC/AC, five-level, single-phase converter prototype with an appropriate test bench.