Comprehensive modelling the operation and climate-weather change effect on the critical infrastructure (CI) safety is presented. The model of the CI safety affected by its outside dependences like climate-weather hazards and operating environment threats is created. Resilience/safety indicators for a CI are defined and a way how to evaluate them in the case of the introduced model is proposed. The procedures are used to the resilience/safety indices determination of the piping affected by the operation and climate-weather change.