This study presents and analyzed the data on GPS observations from 10 permanent stations located in the Northern Tien Shan, Kazakhstan. Analyzed data covers the 6 years, for the period of 2009-2015, which is acceptable for the geodynamic analysis. This investigation based on well-established processing method with GAMIT/GLOBK software package. The velocity field and motion rates of GPS sites were analyzed in the study. All stations showed northwest velocity field with the rate of 2 - 7 mm per year. Motion rates of GPS sites across the Northern Tien Shan decrease northwestward in gradual way. The speeds and directions of the vector fields in South-eastern Kazakhstan do not contrary with modern concepts of regional geodynamics and crustal deformation rates.