Among the most recent new media on which to deliver content is e-books. At their simplest, e-books are digital versions of books that users read on a digital device, such as a computer or a tablet. One particular area of interest in this arena is e-textbooks. For professional communicators who develop e-textbooks, what does the research suggest about the appropriateness of e-texts, design considerations, and effective strategies for presenting content? This preliminary integrative literature review addresses that question.