Anatomy-guided brain PET imaging incorporating a joint prior model | IEEE Conference Publication | IEEE Xplore

Anatomy-guided brain PET imaging incorporating a joint prior model


Abstract:

We proposed a maximum a posterior (MAP) framework for incorporating information from co-registered anatomical images into PET image reconstruction through a novel anato-f...Show More

Abstract:

We proposed a maximum a posterior (MAP) framework for incorporating information from co-registered anatomical images into PET image reconstruction through a novel anato-functional joint prior. The characteristic of the utilized hyperbolic potential function is determinate by the voxel intensity differences within the anatomical image, while the penalization is computed based on voxel intensity differences in reconstructed PET images. Using realistic simulated short time 18FDG PET scan data, we optimized the performance of the proposed MAP reconstruction with the joint prior (JP-MAP), and compared its performance with conventional 3D maximum likelihood expectation maximization (MLEM) and MAP reconstructions. The proposed JP-MAP reconstruction algorithm resulted in quantitatively enhanced reconstructed images, as demonstrated in extensive 18FDG PET simulation study.
Date of Conference: 29 April 2014 - 02 May 2014
Date Added to IEEE Xplore: 31 July 2014
Electronic ISBN:978-1-4673-1961-4

ISSN Information:

Conference Location: Beijing, China

References

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