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A kernel-based framework for intra-fractional respiratory motion estimation in radiation therapy | IEEE Conference Publication | IEEE Xplore

A kernel-based framework for intra-fractional respiratory motion estimation in radiation therapy


Abstract:

In radiation therapy, tumor tracking allows to adjust the beam such that it follows the respiration-induced tumor motion. However, most clinical approaches rely on implan...Show More

Abstract:

In radiation therapy, tumor tracking allows to adjust the beam such that it follows the respiration-induced tumor motion. However, most clinical approaches rely on implanted fiducial markers to locate the tumor and, thus, only provide sparse information. Motion models have been investigated to estimate dense internal displacement fields from an external surrogate signal, such as range imaging. With increasing surrogate complexity, we propose a respiratory motion estimation framework based on kernel ridge regression to cope with high-dimensional domains. This approach was validated on five patient datasets, consisting of a planning 4DCT and a follow-up 4DCT for each patient. Mean residual error was at best 2.73 ± 0.25 mm, but varied greatly between patients.
Date of Conference: 18-21 April 2017
Date Added to IEEE Xplore: 19 June 2017
ISBN Information:
Electronic ISSN: 1945-8452
Conference Location: Melbourne, VIC, Australia

References

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