With data volume growing exponentially in today's era, modern computing systems are increasingly bottlenecked and consistently burdened by the costs of data movement. Driven by the development of emerging non-volatile memory (NVM) technologies and by the increasing demand for high throughput in big data applications, considerable research effort has gone into embedding computing in memory and exploiting parallelism in data-intensive workloads to address the “memory wall” bottleneck. In this work, we propose a non-volatile memory design which leverages run-time reconfigurability of peripheral circuits to perform various in-memory computations like that of a field-programmable gate array (FPGA). Our architecture allows this intelligent storage system to operate as both a main memory and an accelerator for memory-intensive applications such as matrix multiplication, database query and artificial neural networks.