This paper proposes a MOSFET-only voltage reference using the standard 1.2-V MOSFET based on the 65nm CMOS technology, which achieves a power supply voltage operating range of 0.65 V to 2.5 V and the line regulation is 443μV/V. This work demonstrates the technique to achieve a low temperature coefficient and the function of offset voltage cancellation by ZTC-MOS, therefore, the effects of the offset voltage are eliminated. Monte Carlo simulation verifications were conducted based on the TSMC CMOS 65-nm process. Within the temperature range of -40 °C to 150 °C, the voltage reference is 507.4 mV and the temperature coefficient is 23.88ppm/°C in a 160-run Monte Carlo simulation. The overall power consumption is only 6.825 μW at 0.65 V supply under the TT corner and the temperature is set in the typical 27°C.