Conventional data bus inversion (DBI) AC encoding reduces the number of data transitions between current data and previous data by inverting current data. However, if a serializer or a de-serializer (SERDES) is located in the middle of data bus, the DBI applied data correlation is disrupted and DBI AC encoding cannot reduce the number of data transitions any more. In this paper, we present a novel DBI encoding that effectively reduces the number of transitions on the SERDES containg data bus. The proposed scheme determines the inversion status of current data in consideration of previous data both before and after SERDES. As a result, whereas the conventional DBI AC encoding reduces the number of data transitions on entire SERDES-containing data bus by 2.8824%, the proposed encoding scheme achieves 8.3670% of reduction rate.