A high-speed and power-efficient heterogeneous octa-core CPU complex is realized in a 7nm FinFET process. On-chip sensors that handle guard band in terms of process (V_PGB), voltage, temperature (V_TGB), and aging (V_AGB) are designed for power enhancement in dynamic frequency and voltage scaling (DVFS). A process sensor (P-sensor) is used to determine per-die V_PGB for Smartphone operation voltage (V_sov) with machine learning (ML). A temperature sensor (T-sensor) senses run-time local thermal and temperature inversion (T-inversion) to scale V_TGB in DVFS. An aging sensor (A-sensor) converts cell degradation to corresponding V_AGB for aging compensation. Lastly, a voltage sensor (V-sensor) sustains system stability against supply noise. With sensor assistance, the CPU performs up to 2.8GHz speed with 13% power improvement in a fully integrated 5G multi-mode Smartphone SoC that supports the sub-6GHz band with 2.6Gbps upload and 4.7Gbps download speeds.