DNA-sequence analysis using Markov chain models | IEEE Conference Publication | IEEE Xplore

DNA-sequence analysis using Markov chain models


Abstract:

The statistical structure of DNA-sequences is of a great interest to molecular biology, genetics and the theory of evolution (see Chen and others, GIW-99, 1999, Aktulga a...Show More

Abstract:

The statistical structure of DNA-sequences is of a great interest to molecular biology, genetics and the theory of evolution (see Chen and others, GIW-99, 1999, Aktulga and others, EURASIP J. of Bioinformatics and Systems Biology, 2007, Li, Computers and Chemistry , 1997). One of the approaches is a sequence modeling using Markov processes of different orders, and further statistical estimation of their parameters (see Simons and others, JSPI , 2005). In this paper we use firstly the test for the serial independence from Ryabko, Astola (Stat. Methodology, 2006) to estimate the ldquomemoryrdquo (or connectivity) of genetic texts and secondly we apply the homogeneity test for solving the DNA-based problem connected to the phylogenetic system of various organisms.
Date of Conference: 05-09 May 2008
Date Added to IEEE Xplore: 25 July 2008
ISBN Information:
Conference Location: Porto, Portugal

References

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