This paper presents the Multimod Application Framework, a software framework for the rapid development of computer-aided medicine applications. This framework, distributed under an open source licence, is being developed as part of the Multimod Project, a multi-national research endeavour partially supported by the European Commission through the Fifth Framework Programme. This application framework provides an effective re-use model for visualisation and data-processing algorithms that may be incorporated into the framework with moderate overhead and then made available to the biomedical research community as part of a complete set of applications.