This is Part II of the double-part Special Issue (SI) on Positioning and Sensing Over Wireless Networks. The two-part SI aims to bring cutting-edge and novel contributions on positioning and sensing over wireless networks for future and emerging applications. The accepted 51 papers are arranged into eight groups: 1) fundamental performance analysis and optimization; 2) positioning and sensing with cellular networks; 3) positioning and sensing with WiFi networks; 4) positioning and sensing with emerging communication technologies; 5) positioning and sensing applications; 6) cooperative positioning and sensing; 7) reconfigurable intelligent surfaces (RIS)-assisted positioning and sensing; and 8) privacy and security. The contributions made by the papers in Part II are summarized as follows, which correspond to the last four paper groups.