Knowledge management is the further development of management discipline. Teaching management in colleges and universities is fundamentally the management of knowledge. Building teaching management system based on knowledge management is an inevitable choice in colleges and universities. Starting with improving management execution, this article focuses on ideas and methods on the construction of teaching management system basing on knowledge management. From the meaning of knowledge management, this article builds a framework model of teaching management system and designs the five functions of teaching management system platform, introduces the implementation of teaching management system at Beijing Jiaotong University, and further makes recommendation for promoting the implementation of knowledge management in colleges and universities.