The two title concepts have been evolving rather rapidly, but independent of each other. The Wasserstein barycenter, on one hand, has mostly made its appearance in image processing as it can describe a measure of similarity between images. Its minimization might, for example, suggest the best match in image alignment. On the other hand, MMOSPA estimation has been applied largely to multi-target tracking. The Optimal Sub-Pattern Assignment (OSPA) measures the distance between two sets and the Mean OSPA (MOSPA) can be minimized to give the Minimum MOPSA (MMOSPA), which improves MMSE estimation of the target locations when the labeling of the targets in the set is not important. Approximate and exact algorithms have evolved for both Wasserstein barycenters and MMOSPA estimation. Here, we draw connections between the two perspectives and elaborate how they can benefit from each other.