This tutorial deals with the increasing number of cyber attacks in industrial control system which lead to increasing economical damage. The authors focus on the most relevant topics including how to design such systems in future with the goal of higher safety and security. The reader will first learn the basics like the deployed architectures and system layers after which the discussion turns to design aspects, intrusion detection and prevention followed by a survey of current research trends. -Jörg Henkel, Karlsruhe Institute of Technology.