The main objective of the study is to analyze the importance and benefits of using a Hospital Management system and design, develop and asses the interfaces and its data processing performance in order to improve the efficiency of the polyclinic management system. Within the reviewed published literature have been evidenced that there is a lot of published research on usability of user interfaces but not sufficient enough regarding the assessment of user interface performance. The research study aim and goal is to present coherent ways to assess the interface performance by incorporating the Wilcoxon signed-ranks test and assessment of usability issues. Final objective is to investigate the importance of data processing efficiency and effectiveness for polyclinic management system and use these insights to improve the system. The aim of the test was to compare participants' performance in the two conditions to investigate the difference between the scores obtained and assess the data processing efficiency. This test is the non-parametric equivalent of the related t-test. The example used here are data from a group of participants who used two different methods of interaction. After using each version the participants have been used to assess different dimensions of the usability of the system, learn ability, efficiency, visibility, alternative flows, performance, etc. Insights and recommendations are provided, argumented and discussed.