With advances in robotics and communications technology, the demand for the capability to perform measurements on site and instantaneously obtain results to assess biological systems and human health conditions is rapidly growing. In order to meet this demand, we have developed a biological reaction analyses system comprising a surface plasmon resonance total reflection attenuation microscope and an integrated fast capillary injection microfluidic device. This system enables us to not only measure the concentration of biological target molecules but also determine the hydrodynamic parameters of the sample. For example, we can measure viscosity, diffusion coefficients, and blood coagulation reaction rates in the fluidic device within a few seconds.