The usefulness of the availability of some guidelines to manage and control the informative flow deriving from measurements to be used in an Industry 4.0 scenario has been already discussed in [1]. In this work, it has been highlighted that having reliable and efficacious guidelines for the management of the informative flow deriving from measurements implies both formal and substantial actions, with reference to the canonical techniques for data management and the issues connected to a mechatronic system [1]. Formal actions focus on the fulfillment of particular aspects which are considered as prerequisites for the application of the data-processing procedure (e.g., avoiding formal errors in data translation and integration). Substantial actions are linked to the physical interpretation of the monitored phenomena and stress the physical meaning of data and of processing operations.