The paper presents a comparison of tuning procedures for a multi-region fuzzy-logic controller used for nonlinear process control. This controller is composed of local PID controllers and fuzzy-logic mechanism that aggregates local control signals. Three off-line tuning procedures are presented. The first one focuses on separate tuning of local PID controllers gains in the case when the parameters of membership functions of fuzzy-logic mechanism are know a priori. The second one consists of two major steps. In the first step, the local PID controllers gains are calibrated and in the next step the parameters of membership functions of fuzzy-logic mechanism are tuned. The third one focuses on tuning of PID controllers gains and membership functions parameters jointly. These procedures exploit evolutionary algorithm to optimize the performance of the multi-region fuzzy-logic controller with respect to integral quality criterion such as Integral Absolute Error (IAE). Effectiveness of these procedures is verified based on a well known from literature continuous nonlinear pH neutralization reactor model. For comparison a single PID controller tuned for specific work point is also taken into account.