In this paper we propose a Lossless data compressor in high level throughput using re programable FPGA technology. Real time data compression is expected to play a crucial role in high rate data communication applications. Most available approaches have largely overlooked the impact of mixed pixels and subpixel targets, which can be accurately modeled and uncovered by resorting to the wealth of spectral information provided by hyperspectral image data. In this paper, we proposed an FPGA-based data compressor on the concept of CAM and Dictionary based compression technique has been proposed in this paper. It has been implemented on a Xilinx Spartan3 -II FPGA formed by several millions of gates, and with high computational power and compact size, which make this reconfigurable device very appealing for onboard, real-time data processing.