Molecular delivery and transfection by laser-induced oscillating microbubbles | IEEE Conference Publication | IEEE Xplore

Molecular delivery and transfection by laser-induced oscillating microbubbles


Abstract:

Exogenous molecules were successfully delivered into localized single mammalian adherent cells with oscillating microbubbles induced by microsecond laser pulses. The shea...Show More

Abstract:

Exogenous molecules were successfully delivered into localized single mammalian adherent cells with oscillating microbubbles induced by microsecond laser pulses. The shear stress due to the oscillation of the microbubble causes the poration of a nearby cell. Specific single cells can be porated by adjusting the laser position to create the microbubbles beneath the target cell. The poration of localized single cells was demonstrated with the delivery of 500-kDa FITC-Dextran dye and 16-kb plasmids.
Date of Conference: 13-16 April 2014
Date Added to IEEE Xplore: 25 September 2014
Electronic ISBN:978-1-4799-4726-3
Conference Location: Waikiki Beach, HI, USA

References

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