Analysis of a baroreflex model for the study of the chronotropic response to vagal nerve stimulation | IEEE Conference Publication | IEEE Xplore

Analysis of a baroreflex model for the study of the chronotropic response to vagal nerve stimulation


Abstract:

This paper describes the integration of computational models of the cardiovascular system, the cardiac electrical activity and the baroreceptor reflex of the autonomic ne...Show More

Abstract:

This paper describes the integration of computational models of the cardiovascular system, the cardiac electrical activity and the baroreceptor reflex of the autonomic nervous system, with a model representing vagal nerve stimulation (VNS). Sensitivity analyses are performed in order to find the model parameters that produce significant effects on heart rate (chronotropic effect). The most significant parameters are adjusted in order to reproduce real data acquired from sheep suffering from heart failure, during VNS periods. Results show the potential of the model to generate realistic chronotropic responses to VNS.
Date of Conference: 22-24 April 2015
Date Added to IEEE Xplore: 02 July 2015
Electronic ISBN:978-1-4673-6389-1

ISSN Information:

Conference Location: Montpellier, France

References

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