Diabetes remains a common autoimmune disease that poses a difficulty for many in everyday life. Automated monitoring and insulin administering devices alleviate this burden, however, bring extra costs such as a commercial insulin pump and glucose monitoring device to an already expensive condition. There exists a popular open source framework to bring these costs down by replacing the locked-in complete commercial solutions, but approval from governing bodies lags, which when approved would help to improve confidence in using the framework. This work introduces a simple software-in-the-loop (SIL) connection to pair the open-source framework with an established and approved dynamical metabolic simulator with the goal of showing reliability and moving the project closer to governmental approval. Simultaneously, it allows users to test their home-built constructions without needing to use it on a real person first. The presented SIL connection is demonstrated on a simple 24 h simulation.