Balancing high levels of performance and reduced costs has become a crucial goal for organizations. Managers nowadays thrive to achieve a competitive advantage through the optimization of the supply chain distribution network (DN). This work proposes a decision making approach for choosing the right DN. Based on prioritized criteria such as SC responsiveness and costs, it allows comparing different distribution networks and selecting the most appropriate one; in two cases of prioritization of the decision maker. The ranking of these alternatives is done through the application of the multi-criteria decision analysis (MCDA) method AHP (Analytic Hierarchy Process).