In this study, the relative sensitivity coefficient of the proposed hexagonal shaped photonic crystal fiber (PCF) has been investigated by employing the full vectorial finite element method (FEM). Propagation loss of the three different liquid analyte with 35 elliptical air holed PCF over wide wavelength range has been investigated. Also, the applications and the propagation characteristics of the proposed PCF structure which occurs with the interaction of the fundamental mode and the liquid filled holes have been discussed.