Malocclusion has a high prevalence in the population, which seriously affects patients’ oral and mental health. Angle’s classification is a widely accepted diagnostic standard for malocclusion, either requiring professional intervention and complicated procedures, or increasing radiation risks. This paper proposes a new method of Angle’s classification based on occlusal contact information to realize the automatic Angle’s classification. Firstly, a novel bite force measurement device is used to record the occlusal data of subjects with different occlusal categories, Meta-analysis evaluated several occlusion quantitative evaluation indicators. Then, the imbalance of the data set is improved by oversampling and popular machine learning models are used for training and performance evaluation. The result shows that the accuracy of the random forest model combined with occlusal contact information reaches 87.83%, and the performance of other evaluation indexes is good. It is demonstrated that machine learning models can be applied to Angle’s classification and shows the great potential of occlusal contact information in the aided diagnosis of oral diseases.