Supply chain transformation is to fundamentally rethink and radically redesign supply chain strategy, organization, processes and IT system(s) with the target of improving supply chain performance. This paper presents an integrated platform and a comprehensive methodology IBM Supply Chain Process Modeler (SCPM) for process-centric supply chain transformation. In the this methodology, the supply chain transformation is progressing along with the life cycle of business process management, from business process modeling, analyzing to optimizing or restructuring. The other contribution of the paper is the seamless integration of business process management tool and process execution IT system. Based on the integration, the huge gap between process model and execution system is closed and supply chain transformation decisions are realized in operation.