With the fast development of Internet and its data scale, B2B (Business to Business), whose speed and high availability advantage is based on Internet, is eroding more and more market share of traditional business. In recent years, the new data processing technologies, such as cloud computing, assure the enhancement of computer's computing capacity; it has become possible for researchers to process and analyze the massive business data, including large scale customer data, and large scale commodity information. A new B2B platform frame, based on cloud computing with less running time and better response efficiency, is proposed here to promote transaction handle efficiency. By adoption of complex network theory and cloud computing technology, the new platform has been evaluated to decrease transaction handle time, and make more benefits.