This note is intended to investigate noise-to-state stability for random nonlinear systems with state-dependent switching. Under some mild and easily verified conditions, the existence of global solution to random switched systems can be proved. Based on a reasonable requirement for the random disturbance, the criteria on noise-to-state stability of random switched systems are presented by the aid of single Lyapunov function technique. The reasonability of the obtained results is illustrated by using a mechanical model in random vibration environment.