In this correspondence we consider the problem of the construction of efficient sequential fault location experiments for permanent faults. The construction of optimum sequential experiments is an NP-complete problem and, therefore, a heuristic approach for the design of near-optimum sequential experiments is considered. The approach is based on information theoretic concepts and the suggested algorithm for the construction of near-optimum sequential fault location experiments is systematic, has a sound theoretical justification, and yet has low design complexity.