Proactive caching has emerged as a promising solution to reduce the content access latency in radio access networks (RANs), thereby attracting considerable attention in the era of 6G research. It allows base stations to push popular content items to mobile users’ devices proactively. Therefore, a cached-enabled RAN may serve a user by either on-demand transmission or proactive content placement, which share a common radio spectrum. How to efficiently schedule proactive caching and on-demand transmission then becomes a challenging issue that remains open. In this paper, we present a unified framework for joint scheduling of caching and on-demand transmission. In particular, we formulate a Markovian queueing model to analyze the average delay and power consumption of the proposed scheduling policy, which are then jointly minimized via linear programming (LP). Furthermore, a low-complexity heuristic scheduling policy is conceived to strike a sub-optimal tradeoff between delay and power based on greedy algorithms. Simulation results shall demonstrate that the overall service latency of a RAN can be substantially reduced by judiciously designing joint scheduling of caching and on-demand transmission.